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Zymeworks Presents Phase 1 ZW191 Activity in Resistant Ovarian Cancer
The heavily pretreated study population had platinum-resistant disease. The response-rate analysis focused on high-grade serous ovarian cancer.

Zymeworks Inc. presented Phase 1 dose-optimization data for ZW191 on Oct. 24, showing anti-tumor activity in heavily pretreated patients with platinum-resistant ovarian cancer; the drug targets folate receptor alpha (FRα).
ZW191 is an investigational antibody-drug conjugate. The response-rate analysis focused on high-grade serous ovarian cancer.