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Genmab and Incyte Plan Phase 1/2 Trial for KRAS-Mutated Metastatic Colorectal Cancer
The study will combine petosemtamab and INCB161734 with chemotherapy as a potential first-line treatment.

Genmab A/S and Incyte will test a drug combination in a Phase 1/2 study for metastatic colorectal cancer with a KRAS G12D mutation, evaluating it as a potential first-line treatment.
The combination will include petosemtamab, Genmab’s investigational drug, and INCB161734, Incyte’s investigational drug, alongside chemotherapy.